I've tried moving my card to another PCI slot. No conflicts, nothing. Don't get me wrong, I don't doubt M-Audio are a good brand its just a pain in the arse when something pretty important doesn't work in your pretty stable setup. . Again, this is just my experience and may not be the case across the board.

I've used the supplied drivers and the official update but no joy... I'm gonna have to bite the bullet and ring their technical support number.