I love Reason, IMO its alot better than Fruity Loops although there are some features of FL that are superior!
It took me a day to get some sounds out of it, a couple weeks to make a track, and after a few months I'm very proficient with it. It is cool tho because it hides alot of complexity under a simple interface.
I hear Cubase is better but... it always crashes my computer so I dunno