I've screwed around with it a little bit before - but don't really know how to give you some tips to get started... it really requires synthesis generation knowledge and time. (which i never had and so I gave it the arse). It's very similar to the nord software for the modular's - perhaps try and find some tutorials on the nord stuff and adapt it to Max/MSP... it's all too much of a waste of time for me - i've got plenty of synths and vst's, don't have the need to be screwing around building stuff from scratch. i understand the appeal though - good luck :)
machina