If u r using audio (which is kinda obvious from yer question).. u can even benefit from exporting the audio mix down to 32 bit floating point 96 Khz... (if yer sound card can support it ... otherwise don't bother).. that is if u plan 2 further process it (in that case don't use dither)... at the very last stage master down to 44.1khz (for CD)... maybe 48 Khz (4 vinil)... 16 bits should b yer number (but some mastering houses/ mastering plants already take 24 bits and so)..

then again most humans won't know the difference between 44.1 -96khz..

Z