Dunno never used them. Used Cubase on an Atari before PCs were common, the Logic Audio from version 2 till version 4 and now we're on a Mac, so never really played with those things. On the other hand I have a mate who gets some fantastic results out of Reason.

Dunno - I reckon you'd probably do fine with any of them - they all seem to take VST plugins and things, but if I was going to start again I'd probably still learn a audio/sequencer package Cubase/Logic/Nuendo/Protools or something, although occasionally the completely blank sheet of paper they give you is a bit daunting ... like now when I should be getting on with some work!

I'm sure someone else on the forum will have an opinion that differs tho :)